ARD-2128

• Target:

  PROTACs|||Androgen Receptor

• Related Pathways:

  PROTAC|||Endocrinology/Hormones

• Purity:

  0.9972

• Bioactivity:

  ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) that degrades the androgen receptor (AR), effectively reducing AR protein levels, suppressing AR-regulated gene expression in tumor tissues, and inhibiting tumor growth without evident toxicity. This compound holds promise for prostate cancer research.

• Smiles:

  O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CCC(CN5CCN(CC5)C6=CC=C(C(N[C@@H]7C(C)(C)[C@@H](OC8=CC(Cl)=C(C#N)C=C8)C7(C)C)=O)C=C6)CC4

• Molecular Formula:

  C45H50ClN7O6

• Molecular Weight:

  820.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2222111-87-5