PPAR? agonist 9

• Target:

  PPAR

• Related Pathways:

  DNA Damage/DNA Repair|||Metabolism

• Bioactivity:

  PPAR? agonist 9 (compound 21), with an EC50 of 3.6 nM, effectively decreases serum MCP-1 concentrations in mice and significantly reduces atherosclerotic development in the LDLr-KO model with a 50-60% inhibition rate in vivo [1].

• Smiles:

  C(COC1=CC(CC(O)=O)=CC(Cl)=C1)C2(CCN(CC2)C=3SC=4C(N3)=CC=C(C(F)(F)F)N4)N5CCCC5

• Molecular Formula:

  C26H28ClF3N4O3S

• Molecular Weight:

  569.04

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  928023-21-6