HDAC-IN-60

• Target :

  Apoptosis|||HDAC

• Related Pathways :

  Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair

• Bioactivity :

  HDAC-IN-60 (compound 21a), a potent histone deacetylase (HDAC) inhibitor, promotes intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers mitochondria-related apoptotic pathways, leading to cell apoptosis [1].

• Smiles :

  O(C)C1=C(OC)C=C(CCC2=CC(NCC(NO)=O)=C(OC)C=C2)C=C1OC

• Molecular Formula :

  C20H26N2O6

• Molecular Weight :

  390.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2944459-58-7