Relamorelin TFA

• CAS Number :

  2863659-22-5

• Target :

  GHSR

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a potent and selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR), exhibiting a K_i of 0.42 nM for the GHS-1a receptor. This compound can cross the blood-brain barrier and effectively increases growth hormone levels while promoting faster gastric emptying, showing significant research potential for conditions such as cachexia, gastroparesis, and disorders related to gastric/intestinal motility [1] [2] [3] [4] [5].

• Smiles :

  C(C(O)=O)(F)(F)F.C([C@@H](NC([C@@H](CC=1C=2C(SC1)=CC=CC2)NC(=O)C3CCNCC3)=O)C(N[C@H](C(NC4(C(N)=O)CCNCC4)=O)CC5=CC=CC=C5)=O)C=6C=7C(NC6)=CC=CC7

• Molecular Formula :

  C45H51F3N8O7S

• Molecular Weight :

  905

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C