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RTDLDSLRTYTL TFA

CAT: 0931-T83736-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T83736-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
RTDLDSLRTYTL is a ligand for αVβ6 integrin, exhibiting selective inhibition of fibronectin's binding to αVβ6 integrin with considerably less effect on the interactions between vitronectin and αVβ3 or αVβ5, as well as fibrinogen and αIIβ3 (IC50s = 0.02, >50, >50, and >50 μM, respectively) . Additionally, it prevents HT-29 colon cancer cells from binding to fibronectin in a concentration-dependent fashion.
Smiles
OC(C(F)(F)F)=O.OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CC(C)C)=O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C62H104N18O22.XCF3COOH
Molecular Weight
1453.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C