Relamorelin acetate

• Target:

  GHSR

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR) . It exhibits a high affinity for the GHS-1a receptor, with a Ki value of 0.42 nM. Notably, Relamorelin acetate can cross the blood-brain barrier and target the central nervous system. This compound effectively increases growth hormone levels and promotes faster gastric emptying. Due to these properties, Relamorelin acetate holds promise for its potential applications in research related to cachexia, gastroparesis, and gastric/intestinal dysmobility disorders [4] [5].

• Smiles:

  CC (O) =O.NC (=O) C1 (CCNCC1) NC (=O) [C@H] (Cc1ccccc1) NC (=O) [C@@H] (Cc1c[nH]c2ccccc12) NC (=O) [C@@H] (Cc1csc2ccccc12) NC (=O) C1CCNCC1

• Molecular Formula:

  C45H54N8O7S

• Molecular Weight:

  851.04

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1809080-14-5