LAP TFA

CAT: 0931-T83714-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T83714-01Size:1 mg
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Bioactivity
Lupus autoantigen peptide (LAP), a derivative of the autoantigen La found in systemic lupus erythematosus (SLE) patients, spans amino acids 11-28 of La and functions as an antiviral peptide. It primarily blocks the hepatitis C virus (HCV) from interacting with internal ribosome entry site (IRES) trans-acting factors (ITAFs), notably the polypyrimidine tract-binding protein (PTB) and poly (rC) -binding protein 2 (PCBP2) . In a Huh7 cell-based reporter assay, LAP at a concentration of 60 µM effectively hampers HCV IRES-mediated translation, a process reversible by adding recombinant forms of PTB and PCBP2.
Smiles
OC(C(F)(F)F)=O.C[C@H](N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@@]([H])([C@H](CC)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@]([H])([C@H](CC)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)CC(O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)CC4=CC=C(C=C4)O)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)CC5=CNC=N5)=O)CS[H])=O)=O)CCCCN)=O)=O)CCC(O)=O)=O)=O)=O
Molecular Formula
C99H141N23O27S.XCF3COOH
Molecular Weight
2117.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS6233371-01IFIT3 (Interferon-induced Protein with Tetratricopeptide Repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60kD Protein, IFI-60K, Interferon-induced Protein with Tetratricopeptide Repeats 4, IFIT-4, Retinoic Acid-induced Gene G-Protein, P60, RIG-G, CIG
MBS6235285-01SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Alpha-SGT, Vpu-binding protein, UBP, SGT, SGT1) (MaxLight 750)
MBS6235917-01TSPAN1 (Tetraspanin-1, Tetraspan NET-1, Tetraspanin TM4-C) (MaxLight 750)
MBS6235920-01TSPAN8 (Tetraspanin-8, Tspan-8, Transmembrane 4 Superfamily Member 3, TM4SF3, Tumor-associated Antigen CO-029) (MaxLight 750)
MBS6241195-01TSPAN2 (Tetraspanin 2, 6330415F13Rik, FLJ12082, TSN2, TSPAN-2) (MaxLight 750)
MBS6241196-01TSPAN32 (Tetraspanin 32, FLJ17158, FLJ97586, MGC22455, PHEMX, PHMX, TSSC6) (MaxLight 750)
MBS6247488-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (AP)
MBS6249514-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (FITC)
MBS6252216-01Tetrahydrocannabinol (THC) (PE)

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