STING agonist-28

CAT: 0931-T75096-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T75096-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2868261-50-9

Target

STING, Others

Related Pathways

Others, Immunology/Inflammation

Bioactivity

STING agonist-23 (CF510) is a non-nucleotide, small-molecule activator of the STING pathway. It initiates the phosphorylation of STING, TBK1, and IRF3, enhancing the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. Notably, it demonstrates activity against SARS-CoV series strains [1].

Smiles

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCN7CCOCC7

Molecular Formula

C39H46N14O6

Molecular Weight

806.87

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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