STING agonist-28

• Target:

  STING|||Others

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  STING agonist-23 (CF510) is a non-nucleotide, small-molecule activator of the STING pathway. It initiates the phosphorylation of STING, TBK1, and IRF3, enhancing the production of IFN-?, IL-6, CXCL-10, TNF-?, ISG-15, and CCL-5 in tumor cells. Notably, it demonstrates activity against SARS-CoV series strains [1].

• Smiles:

  C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCN7CCOCC7

• Molecular Formula:

  C39H46N14O6

• Molecular Weight:

  806.87

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2868261-50-9