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STING agonist-24

CAT: 0931-T75092-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T75092-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408722-91-6
Target
Others, STING
Related Pathways
Immunology/Inflammation, Others
Bioactivity
STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells, demonstrating activity against SARS-CoV series strains [1].
Smiles
C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OC
Molecular Formula
C34H37N13O5
Molecular Weight
707.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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