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HAT-SIL-TG-1&AT

CAT: 0931-T74800-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74800-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
JAK, STAT, Others
Related Pathways
JAK/STAT signaling, Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Others
Bioactivity
HAT-SIL-TG-1&AT, a hypoxia-activated prodrug, functions as a Janus tyrosine kinase (JAK) inhibitor demonstrating antitumor effects by inhibiting JAK-STAT signaling within tumor tissues. It also suppresses the proliferation of HEL cells and downregulates phosphorylated STAT3/5 in hypoxic conditions.
Molecular Formula
C60H69N17O11S
Molecular Weight
1236.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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