TG 100572

• Target:

  VEGFR|||FGFR|||PDGFR|||Src

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases (IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFR?, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively) .

• Smiles:

  ClC1=C(C2=CC3=C(C(C)=C2)N=C(NC4=CC=C(OCCN5CCCC5)C=C4)N=N3)C=C(O)C=C1

• Molecular Formula:

  C26H26ClN5O2

• Molecular Weight:

  475.97

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  867334-05-2