TG-89

• Target :

  JAK|||c-RET|||FLT

• Related Pathways :

  Angiogenesis|||Chromatin/Epigenetic|||Apoptosis|||Stem Cells|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

• Purity :

  0.988

• Bioactivity :

  TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 ?M against JAK2, showing anticancer activity in the treatment of ovarian and cervical cancer.

• Smiles :

  Cc1cnc(Nc2cccc(CN3CCOCC3)c2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C

• Molecular Formula :

  C26H34N6O3S

• Molecular Weight :

  510.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  936091-56-4