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12-Hydroxynevirapine

CAT: 0931-T74717-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74717-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
133627-24-4
Target
Others, Drug Metabolite
Related Pathways
Others, Metabolism
Bioactivity
12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP), a significant oxidative metabolite of Nevirapine—an antiviral drug for HIV-1 infections known for potential idiosyncratic hepatotoxicity and skin rashes—undergoes bioactivation through sulphotransferases (SULTs) in the liver and skin to form the reactive species 12-Sulphoxy-nevirapine [1] [2].
Smiles
OCc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12
Molecular Formula
C15H14N4O2
Molecular Weight
282.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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