Mtb-IN-12

CAT: 0931-T211382-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211382-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Cytochromes P450|||Antibacterial
Related Pathways
Microbiology/Virology|||Metabolism
Bioactivity
Mtb-IN-12 (Compound 5m) is a dual-target inhibitor that acts on the Mycobacterium tuberculosis enzymes CYP125 with a dissociation constant (KD) of 40 nM and an inhibition constant (KI) of 0.1 ?M, and CYP142 with a KD of 160 nM and a KI of 0.05 ?M. It effectively inhibits both drug-sensitive and multidrug-resistant strains of the tuberculosis bacterium, with low toxicity to macrophages, making it useful for studying anti-tuberculosis treatments.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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