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Ferroptosis-IN-12

CAT: 0931-T200665-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200665-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ferroptosis
Related Pathways
Apoptosis
Bioactivity
Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP) . This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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