XY-06-007

CAT: 0931-T74380Size: 5 mgDry Ice: NoHazardous: No

CAT#:0931-T74380Size:5 mg

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PRICE

AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

1 / 1

CAS Number

2757045-94-4

Target

PROTACs|||Epigenetic Reader Domain|||Others

Related Pathways

Others|||PROTAC|||Chromatin/Epigenetic

Bioactivity

XY-06-007, a potent and selective bump-and-hole (B&H) PROTAC BRD4 BD1 L94V degrader, exhibits a DC50, 6 h of 10 nM specifically against BRD4 BD1 L94V without degrading off-targets. It also demonstrates favorable pharmacokinetics for in vivo studies [1].

Smiles

[H][C@]1(N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc12)[C@@H](C)C(=O)NCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Molecular Formula

C41H41ClN8O8

Molecular Weight

809.27

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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