XY-52

• Target :

  Others|||Interleukin

• Related Pathways :

  Others|||Immunology/Inflammation

• Bioactivity :

  XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 ?M and 4.59 ?M in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasma sST2 and IFN? biomarkers in a graft versus host disease (GVHD) mouse model [1].

• Smiles :

  CC1=CC([N+]([O-])=O)=CC=C1C2=CC=C(CN3C(C4=CC=CC(N5CC(CC6)NC6C5)=C4)CCC3)N2CC

• Molecular Formula :

  C30H37N5O2

• Molecular Weight :

  499.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C