XY-52

CAT: 0931-T80759-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T80759-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Others, Interleukin

Related Pathways

Others, Immunology/Inflammation

Bioactivity

XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasma sST2 and IFNγ biomarkers in a graft versus host disease (GVHD) mouse model [1].

Smiles

CC1=CC([N+]([O-])=O)=CC=C1C2=CC=C(CN3C(C4=CC=CC(N5CC(CC6)NC6C5)=C4)CCC3)N2CC

Molecular Formula

C30H37N5O2

Molecular Weight

499.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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XY-52

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