Beauverolide Ja

• Target:

  CaMK|||Endogenous Metabolite|||Others

• Related Pathways:

  Neuroscience|||Others|||Metabolism

• Bioactivity:

  Beauverolide Ja, a cyclotetradepsipeptide and secondary metabolite of Isaria fumosorosea [1], functions as a potent inhibitor of calmodulin (CaM), exhibiting a dissociation constant (Kd) of 0.078 ?M and an inhibition constant (Ki) of 0.39 ?M for Ca2+-CaM.

• Smiles:

  [H][C@@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CC(OC1=O)C(C)CCCC)[C@@H](C)CC

• Molecular Formula:

  C35H46N4O5

• Molecular Weight:

  602.76

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  76265-41-3