Beauverolide Ka

• Description :

  Beauverolide Ka, a cyclotetradepsipeptide, is a metabolite of Beauveria bassiana fungus. Beauverolide Ka stimulates glucose uptake in cultured rat L6 myoblasts at 50 μM. Beauverolide Ka exhibits protecting effects on HEI-OC1 cells at 10 μM and shows dose-dependent activity in both L6 myoblasts and myotubes[1][2].

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/beauverolide-ka.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N[C@@H](C(O[C@@H](CC(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N3)=O)=O)[C@@H](C)CCCCCC)=O)[C@@H](C)CC)[C@@H]3CC4=CC=CC=C4

• Molecular Formula :

  C37H50N4O5

• Molecular Weight :

  630.82

• References & Citations :

  [1]Yuan-Fei Zhou, et al. 3-Hydroxy-4-methyldecanoic Acid-Containing Cyclotetradepsipeptides from an Endolichenic Beauveria sp. J Nat Prod. 2021 Apr 23;84 (4) :1244-1253.|[2]Feifei Luo, et al. Differential metabolic responses of Beauveria bassiana cultured in pupae extracts, root exudates and its interactions with insect and plant. J Invertebr Pathol. 2015 Sep;130:154-64.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Microbial Metabolite

• CAS Number :

  [76265-42-4]