Beauverolide Ja

• Description:

  Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea[1].

• UNSPSC:

  12352005

• Target:

  Calmodulin; Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/beauverolide-ja.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@H](C(N[C@](C(OC(CC(N1)=O)C(C)CCCC)=O)([H])[C@@H](C)CC)=O)CC2=CC=CC=C2)[C@@H]1CC3=CNC4=CC=CC=C34

• Molecular Formula:

  C35H46N4O5

• Molecular Weight:

  602.76

• References & Citations:

  Isaria fumosoroseaIsaria farinose

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Microbial Metabolite

• CAS Number:

  [76265-41-3]