Beauveriolide III

• Target:

  Beta Amyloid

• Related Pathways:

  Neuroscience

• Purity:

  0.9948

• Bioactivity:

  Beauveriolide III, a cyclodepsipeptide found in Beauveria fungi, inhibits lipid droplet formation (at 3-10 ?M) and cholesterol synthesis (IC50=0.41 ?M) . This compound also suppresses acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity (IC50=5.5 ?M) and reduces atherosclerotic lesion size in Ldlr-/- and ApoE-/- mouse models (25-50 mg/kg) .

• Smiles:

  C([C@@H]1NC(=O)C[C@@]([C@H](CCCC)C)(OC(=O)[C@@]([C@H](CC)C)(NC(=O)[C@H](C)NC1=O)[H])[H])C2=CC=CC=C2

• Molecular Formula:

  C27H41N3O5

• Molecular Weight:

  487.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  221111-70-2