Beauveriolide I

• Target :

  Others|||Endogenous Metabolite

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 ?M, as well as inhibits cholesterol synthesis (IC50= 0.78 ?M), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 ?M) .2

• Smiles :

  [H][C@]1(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@]([H])(CC(C)C)C(=O)O1)[C@@H](C)CCCC

• Molecular Formula :

  C27H41N3O5

• Molecular Weight :

  487.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  154491-55-1