Beauveriolide I

CAT: 0931-MF-0047814-01Size: 250 µgDry Ice: NoHazardous: No
CAT#:0931-MF-0047814-01Size:250 µg
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CAS Number
154491-55-1
Target
Others|||Endogenous Metabolite
Related Pathways
Others|||Metabolism
Bioactivity
Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 ?M, as well as inhibits cholesterol synthesis (IC50= 0.78 ?M), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 ?M) .2
Smiles
[H][C@]1(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@]([H])(CC(C)C)C(=O)O1)[C@@H](C)CCCC
Molecular Formula
C27H41N3O5
Molecular Weight
487.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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