Beauveriolide I

• Target:

  Others|||Endogenous Metabolite

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 ?M, as well as inhibits cholesterol synthesis (IC50= 0.78 ?M), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 ?M) .2

• Smiles:

  [H][C@]1 (CC (=O) N[C@@H] (Cc2ccccc2) C (=O) N[C@@H] (C) C (=O) N[C@] ([H]) (CC (C) C) C (=O) O1) [C@@H] (C) CCCC

• Molecular Formula:

  C27H41N3O5

• Molecular Weight:

  487.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  154491-55-1