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GNE-2256

CAT: 0931-T73372-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T73372-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2102170-43-2
Target
Others|||IRAK
Related Pathways
NF-?B|||Others|||Immunology/Inflammation
Purity
0.9995
Bioactivity
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
Smiles
N(C(=O)C1=C2N(N=C1)C=CC=N2)C3=C(C=C4C(=C3)CN(C[C@H](C(C)(C)O)F)C4=O)N5CCOCC5
Molecular Formula
C24H27FN6O4
Molecular Weight
482.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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