GNE-2256

• Target:

  Others|||IRAK

• Related Pathways:

  NF-?B|||Others|||Immunology/Inflammation

• Purity:

  0.9995

• Bioactivity:

  GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.

• Smiles:

  N(C(=O)C1=C2N(N=C1)C=CC=N2)C3=C(C=C4C(=C3)CN(C[C@H](C(C)(C)O)F)C4=O)N5CCOCC5

• Molecular Formula:

  C24H27FN6O4

• Molecular Weight:

  482.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2102170-43-2