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CBL 0100 free base

CAT: 0931-T71263-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T71263-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1197996-83-0
Target
HIV Protease, Others, DNA/RNA Synthesis
Related Pathways
Others, Proteases/Proteasome, Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair
Purity
0.9886
Bioactivity
CBL 0100 free base is an HIV-1 transcription inhibitor that blocks HIV-1 replication and reactivation in vitro and in ex vivo models. It targets the chromatin-associated transcription (FACT) complex, reducing the occupancy of RNA Polymerase II and FACT in the HIV-1 promoter region, and can be used as a latency-reversing agent (LRA) in cART therapy.
Smiles
O=C1C2=CC=C3C(C=4C(=CC=C5C(=O)CCC54)N3CCN(CC)CC)=C2CC1
Molecular Formula
C24H26N2O2
Molecular Weight
374.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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