CM-118

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  CM-118 is a potent and selective dual inhibitor of c-Met and ALK which potently abrogates hepatocyte growth factor (HGF) -induced c-Met phosphorylation and cell migration, as well as phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells.

• Smiles :

  O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C=2C=C(C(NC3=CN(C)C(=O)C=C3)=O)N=NC2N

• Molecular Formula :

  C19H16Cl2FN5O3

• Molecular Weight :

  452.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1370652-56-4