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EGFR-IN-118

CAT: 0931-T210366-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210366-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
EGFR-IN-118 (Compound 4a) is an inhibitor of the tyrosine kinase EGFR. It exhibits anticancer properties, effectively inhibiting the proliferation of MCF-7 and PC3 cells, with IC50 values of 2.53 and 3.25 μg/ml, respectively. Additionally, EGFR-IN-118 demonstrates antioxidant activity by inhibiting DPPH free radicals, with an IC50 of 10.04 μg/ml.
Molecular Formula
C26H23N3O2S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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