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LQB-118

CAT: 0931-T200386-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200386-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1219104-20-7
Target
Apoptosis, Reactive Oxygen Species, MMP, GSK-3
Related Pathways
Metabolism, Immunology/Inflammation, Apoptosis, Proteases/Proteasome, Stem Cells, PI3K/Akt/mTOR signaling, NF-κB
Bioactivity
LQB-118, an orally active compound sourced from sandalwood, demonstrates multiple therapeutic capabilities. It has shown proficiency in inhibiting glioblastoma cell migration and inducing apoptosis. Additionally, LQB-118 can curtail both migration and invasion of prostate cancer cells by modulating the AKT/GSK3β pathway and regulating MMP-9/reck gene expression. The compound is also effective against yeast polysaccharide-induced inflammation in both in vivo and in vitro settings. Notably, LQB-118 specifically triggers ROS-mediated and mitochondrial-dependent apoptosis in Leishmania amazonensis, highlighting its potential in studies focusing on inflammation, infections, and various cancers.
Smiles
O=C1C=2[C@@]3([C@@](C=4C(O3)=CC=CC4)(COC2C(=O)C=5C1=CC=CC5)[H])[H]
Molecular Formula
C19H12O4
Molecular Weight
304.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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