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CM-444

CAT: 0931-T210199-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210199-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
DNA Methyltransferase, HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
CM-444 is an inhibitor of HDAC (IC50 ranging from 6 nM to 0.6 μM) and DNA methyltransferase (DNMT, IC50 ranging from 1.8 to 2.3 μM) . This compound induces differentiation in acute myeloid leukemia cells, exhibits anti-leukemia activity, and enhances survival rates in mouse models.
Molecular Formula
C27H30N6O5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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