CM-444
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CM-444
Target :
DNA Methyltransferase|||HDACRelated Pathways :
Chromatin/Epigenetic|||DNA Damage/DNA RepairBioactivity :
CM-444 is an inhibitor of HDAC (IC50 ranging from 6 nM to 0.6 ?M) and DNA methyltransferase (DNMT, IC50 ranging from 1.8 to 2.3 ?M) . This compound induces differentiation in acute myeloid leukemia cells, exhibits anti-leukemia activity, and enhances survival rates in mouse models.Molecular Formula :
C27H30N6O5Shipping Conditions :
Cool packStorage Temperature :
-20°C
