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RO27-3225 TFA

CAT: 0931-T70838-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70838-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1373926-49-8
Target
TNF, Melanocortin Receptor, Interleukin, Others
Related Pathways
Apoptosis, Others, GPCR/G Protein, Immunology/Inflammation, Neuroscience
Bioactivity
RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225 shows some activity at the MC1 receptor. Ro 27-3225 reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.
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OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)CC(N)=O
Molecular Formula
C41H53F3N12O8
Molecular Weight
898.9462
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-P2242RO27-3225
HY-P2242A-01RO27-3225 (TFA)
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MBS5789549RO27-3225 TFA (274682-89-2 free base)
MBS3606953RO 27-3225
sc-311523Ro 27-3225 trifluoroacetate salt
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