MK-8666 Tris

• Target :

  Others|||GPCR

• Related Pathways :

  GPCR/G Protein|||Others|||Endocrinology/Hormones

• Bioactivity :

  MK-8666 Tris is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 Tris has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.

• Smiles :

  NC(CO)(CO)CO.[H][C@@]12Cc3cc(OCc4cccc(c4)-c4c(C)cc(OCCCS(C)(=O)=O)cc4C)ncc3[C@]1([H])[C@H]2C(O)=O

• Molecular Formula :

  C33H42N2O9S

• Molecular Weight :

  642.764

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2056254-98-7