MK-8666

• Target :

  Endogenous Metabolite|||Others

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.

• Smiles :

  C(O)(=O)[C@H]1[C@]2([C@@]1(CC=3C2=CN=C(OCC4=CC(=CC=C4)C5=C(C)C=C(OCCCS(C)(=O)=O)C=C5C)C3)[H])[H]

• Molecular Formula :

  C29H31NO6S

• Molecular Weight :

  521.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1544739-76-5