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MK-8527

CAT: 0931-T86907-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T86907-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1810869-23-8
Target
Reverse Transcriptase, HIV Protease, Antiviral
Related Pathways
Microbiology/Virology, Immunology/Inflammation, Proteases/Proteasome
Purity
0.9915
Bioactivity
MK-8527 is an orally active HIV-1 inhibitor and nucleoside reverse transcriptase translocation inhibitor with an IC50 of 0.21 nM. It is phosphorylated intracellularly to its active triphosphate form, exhibiting antiviral activity.
Smiles
NC1=C2C(N(C=C2)[C@@H]3O[C@](C#C)(CO)[C@@H](O)C3)=NC(Cl)=N1
Molecular Formula
C13H13ClN4O3
Molecular Weight
308.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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