TP-051

CAT: 0931-T68535-04Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T68535-04Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

858097-86-6

Target

GPCR

Related Pathways

Endocrinology/Hormones, GPCR/G Protein

Purity

0.9996

Bioactivity

TP-051 is a potent and selective FFAR1 agonist exhibiting a Ki of 16 nM for human FFAR1, with demonstrated ability to enhance insulin secretion in rat insulinoma cells. TP-051 is widely used as a chemical probe for studying free-fatty-acid receptor-mediated pathways in type 2 diabetes and metabolic research.

Smiles

O=C(O)CCC1=CC=C(OCC2=CC=CC(=C2)C3=C(C=C(OC4CCS(=O)(=O)CC4)C=C3C)C)C=C1F

Molecular Formula

C29H31FO6S

Molecular Weight

526.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

3-[4-[[3-[4-(1,1-Dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid

CAS Number	858097-86-6
PubChem CID	11203294
IUPAC Name	3-[4-[[3-[4-(1,1-dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
Molecular Formula	C29H31FO6S
Molecular Weight	526.6
XLogP	5.5
Topological Polar Surface Area	98.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Heavy Atom Count	37
Formal Charge	0
Complexity	818

SMILES

CC1=CC(=CC(=C1C2=CC=CC(=C2)COC3=CC(=C(C=C3)CCC(=O)O)F)C)OC4CCS(=O)(=O)CC4

InChI

InChI=1S/C29H31FO6S/c1-19-14-26(36-24-10-12-37(33,34)13-11-24)15-20(2)29(19)23-5-3-4-21(16-23)18-35-25-8-6-22(27(30)17-25)7-9-28(31)32/h3-6,8,14-17,24H,7,9-13,18H2,1-2H3,(H,31,32)

InChIKey

RPAHCZZXEGWBDL-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 858097-86-6

CID: 11203294

Formula: C29H31FO6S

MW: 526.6

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	526.6
XLogP3	5.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	526.18253804
Monoisotopic Mass	526.18253804
Topological Polar Surface Area	98.3 Å²
Heavy Atom Count	37
Formal Charge	0
Complexity	818
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T68314-01	DG-051
T88788-01	LH2-051
T32242-01	IWP-051
T9901A-1594-01	GNR-051
T70715-01	AQW-051 fumarate
T37477-01	L-858,051 (hydrochloride)
T70429-01	TP-6076
T68869-01	TP-110
T200593-01	TP-DEA2
T9254-01	TP-2857

Alternative Products

Catalog	Name
MBS5811096	TP-051
UBB77029-01	AQW-051
MBS3841899-01	KIN001-051
GTR19211562-01	DG-051
HY-161723-01	LH2-051
HY-117443	IWP-051
HY-P991349	GNR-051
530662	DG-051 HCl
A16923-5	KIN001-051 5mg
A14144-25	FYX 051 25mg

TP-051

Chemical Information

Related Products

Alternative Products

Popular Products