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LH2-051

CAT: 0931-T88788-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88788-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2358754-22-8
Target
Dopamine Receptor, CDK
Related Pathways
Cell Cycle/Checkpoint, Neuroscience, GPCR/G Protein
Bioactivity
LH2-051 is a lysosomal-enhancing lead compound that stimulates lysosomal biosynthesis and the clearance of Aβ aggregates through the dopamine transporter-cell cycle protein dependent kinase 9-transcription factor EB (DAT-CDK9-TFEB) pathway. Demonstrating favorable pharmacokinetic properties in mouse models, LH2-051 has the potential to improve Alzheimer's disease outcomes.
Smiles
O(C=1C=C2C(=CC1OC)C(N(CC2)CC3CCOCC3)CCC4=CNC=5C=CC=CC54)C
Molecular Formula
C27H34N2O3
Molecular Weight
434.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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