LH2-051

• Target:

  Dopamine Receptor|||CDK

• Related Pathways:

  Cell Cycle/Checkpoint|||Neuroscience|||GPCR/G Protein

• Bioactivity:

  LH2-051 is a lysosomal-enhancing lead compound that stimulates lysosomal biosynthesis and the clearance of A? aggregates through the dopamine transporter-cell cycle protein dependent kinase 9-transcription factor EB (DAT-CDK9-TFEB) pathway. Demonstrating favorable pharmacokinetic properties in mouse models, LH2-051 has the potential to improve Alzheimer's disease outcomes.

• Smiles:

  O (C=1C=C2C (=CC1OC) C (N (CC2) CC3CCOCC3) CCC4=CNC=5C=CC=CC54) C

• Molecular Formula:

  C27H34N2O3

• Molecular Weight:

  434.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2358754-22-8