AGG-523

• CAS Number :

  920289-29-8

• Target :

  Others|||Protease

• Related Pathways :

  Others|||Proteases/Proteasome

• Bioactivity :

  AGG-523 is an aggrecanase specific inhibitor that has been shown to attenuate increases in synovial fluid ARG-aggrecan levels following surgically-induced joint instability in the rat MT model. Pharmacologic inhibition of aggrecanase activity in humans using AGG-523 may be an effective treatment for slowing cartilage degradation following joint injury.

• Smiles :

  C(N[C@H](C(NC(CC1=CC=C(F)C=C1)(C)C)=O)CCC(O)=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3

• Molecular Formula :

  C28H29FN2O4

• Molecular Weight :

  476.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C