EM-523

• Description:

  EM-523 is a motilin agonist and an erythromycin derivative. EM-523 has pED50 values of 8.19 and 6.08 for promoting contractions in rabbit small intestinal tissue and human duodenal tissue, respectively. EM-523 can be used in the research of gastrointestinal diseases[1].

• UNSPSC:

  12352005

• Target:

  Motilin Receptor

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Metabolic Disease

• Smiles:

  C[C@]1(OC([C@@H]([C@H]([C@](O)([C@H](OC([C@@H]([C@H]([C@@H]2C)O[C@H]3C[C@](C)([C@H]([C@@H](O3)C)O)OC)C)=O)CC)C)O)C)=C(C1)C)[C@@H]2O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)CC)O

• Molecular Formula:

  C38H67NO12

• Molecular Weight:

  729.94

• References & Citations:

  [1]Depoortere I, et al. The erythromycin derivative EM-523 is a potent motilin agonist in man and in rabbit. Peptides. 1990 May-Jun;11 (3) :515-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [110205-60-2]