SGX-523

• Target:

  P38 MAPK|||c-Met/HGFR|||Raf|||Bcr-Abl

• Related Pathways:

  Tyrosine Kinase/Adaptors|||MAPK|||Angiogenesis|||Cytoskeletal Signaling

• Purity:

  >99.99%

• Bioactivity:

  SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38?, and c-Raf.

• Smiles:

  Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1

• Molecular Formula:

  C18H13N7S

• Molecular Weight:

  359.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1022150-57-7