HIF-2α agonist 2

CAT: 0931-T67831-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T67831-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2750141-15-0

Target

HIF/HIF Prolyl-Hydroxylase, HIF

Related Pathways

Metabolism, Chromatin/Epigenetic, Angiogenesis

Purity

0.9927

Bioactivity

HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A/B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reha-Luc cells. HIF-2α agonist 2 can be used in the study of oxygen metabolism and is closely related to the occurrence of cancer.

Smiles

N(C=1C=2C(S(=O)(=O)N1)=CC=CC2)C3=CC(Br)=CC(Br)=C3

Molecular Formula

C13H8Br2N2O2S

Molecular Weight

416.09

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HIF-2α agonist 2

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