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12 (S) -HHT

CAT: 0931-T41365-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T41365-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
54397-84-1
Target
Endogenous Metabolite, Leukotriene Receptor
Related Pathways
Metabolism, GPCR/G Protein
Bioactivity
12 (S) -HHT (12 (S) -HHTrE), a fatty acid produced via the arachidonic acid metabolic pathway of cyclooxygenase (COX), is an endogenous ligand and agonist of BLT2, and the 12 (S) -HHT/BLT2 axis plays a role in the maintenance of homeostatic aspects of epithelial tissues and in inflammatory responses. 12 (S) -HHT inhibits the p38 MAPK/NF-κB pathway through upregulation of MKP-1, leading to reduced IL-6 synthesis in UVB-irradiated HaCaT cells.
Smiles
[C@@H](/C=C/C=C/C/C=C\CCCC(O)=O)(CCCCC)O
Molecular Formula
C17H28O3
Molecular Weight
280.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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499772ALK1, Recombinant, Human, GST-Tag (Activin A Receptor, Type II-like 1, ACVRL1, ACVRLK1, ALK1, HHT, HHT2, ORW2, SKR3, ALK1, TSR-I) discontinued
351057-01ACVRL1, Recombinant, Human, aa22-118, His-Tag (Serine/threonine-Protein Kinase Receptor R3, ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I)
A0855-91BActivin A Receptor, Type II-like 1 (Activin receptor-like kinase 1, ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, Activin A receptor, type II-like kinase 1) discontinued
147593Activin A Receptor, Type II-like 1, Control Peptide (Activin receptor-like kinase 1, ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, Activin A receptor, type II-like kinase 1)
A135997Dalantercept Biosimilar (, Fusion - [ACVRL1 (activin A receptor like type 1, activin receptor-like kinase 1, ACVRLK1, ALK1, ALK-1, serine/threonine-protein kinase receptor R3, SKR3, HHT, HHT2, ORW2) ]2 - IGHG1 Fc (Fragment constant) )
207471ACVRL1 (Activin A Receptor Type II-like 1, TGF-B Superfamily Receptor Type I, Activin A Receptor, Type II-like Kinase 1, Serine/Threonine-Protein Kinase Receptor R3, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I)

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