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5 (S),12 (S) -DiHETE

CAT: 0931-T37649-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T37649-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
79056-01-2
Target
Others
Related Pathways
Others
Bioactivity
5 (S),12 (S) -DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5 (S),12 (S) -DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12 (S) -HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5 (S),12 (S) -DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.
Smiles
CCCCC\C=C/C[C@H](O)\C=C\C=C/C=C/[C@@H](O)CCCC(O)=O
Molecular Formula
C20H32O4
Molecular Weight
336.472
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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