VVD-442

• CAS Number :

  3055318-88-9

• Target :

  Ras|||PI3K

• Related Pathways :

  PI3K/Akt/mTOR signaling|||MAPK

• Bioactivity :

  VVD-442 is a covalent RAS-PI3K inhibitor that binds covalently to cysteine at position 242 in the RAS-binding domain of PI3Kp110?, thereby inhibiting the interaction between RAS and PI3K. VVD-442 is applicable for research in cancers such as breast cancer.

• Smiles :

  S(=O)(=O)(C1=C(C=C(Br)C=C1)C2=C(Cl)C=CC=C2)N3CCC(C(N[C@@H](/C=C\S(C)(=O)=O)C)=O)(F)CC3

• Molecular Formula :

  C23H25BrClFN2O5S2

• Molecular Weight :

  607.94

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C