VVD-118313

• Target:

  STAT|||JAK|||Interleukin|||Others|||IFNAR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Stem Cells|||Immunology/Inflammation|||Others|||Chromatin/Epigenetic

• Bioactivity:

  VVD-118313 (compound 5a), a potent, selective JAK1 inhibitor, targets an isoform-restricted allosteric cysteine to inhibit JAK1-dependent trans-phosphorylation and cytokine signaling. This compound is utilized in cancer research [1].

• Smiles:

  C(C#C[C@@H]1CN(S(C)(=O)=O)CC1)(=O)N2C[C@@H](CCC2)C3=CC(Cl)=C(Cl)C=C3

• Molecular Formula:

  C19H22Cl2N2O3S

• Molecular Weight:

  429.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2875046-27-6