VVD-118313

CAT: 0931-T62361-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T62361-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2875046-27-6
Target
STAT|||JAK|||Interleukin|||Others|||IFNAR
Related Pathways
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Stem Cells|||Immunology/Inflammation|||Others|||Chromatin/Epigenetic
Bioactivity
VVD-118313 (compound 5a), a potent, selective JAK1 inhibitor, targets an isoform-restricted allosteric cysteine to inhibit JAK1-dependent trans-phosphorylation and cytokine signaling. This compound is utilized in cancer research [1].
Smiles
C(C#C[C@@H]1CN(S(C)(=O)=O)CC1)(=O)N2C[C@@H](CCC2)C3=CC(Cl)=C(Cl)C=C3
Molecular Formula
C19H22Cl2N2O3S
Molecular Weight
429.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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