Basivarsen linker

• Target:

  ADC Linker

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Basivarsen linker is a connector employed in Zeleciment basivarsen, facilitating the attachment of a Fab antibody (Zeleciment) that targets the TfR1 receptor to an antisense oligonucleotide. Zeleciment basivarsen is studied for its potential application in the treatment of myotonic dystrophy type 1 (DM1) .

• Smiles:

  C(OC(NCCOCCOCCOCCOCCC(N)=O)=O)[C@H]1[C@@]2([C@]1(CCC3=C(CC2)N(CCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC4=CC=C(COC(N)=O)C=C4)=O)CCCNC(N)=O)=O)C(C)C)=O)N=N3)[H])[H]

• Molecular Formula:

  C50H81N11O16

• Molecular Weight:

  1092.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2763758-01-4