RBM1-151

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  RBM1-151 is a 1-deoxy derivative and vinyl analog of RBM14-C12, serving as a fluorescent substrate for amidases (Ex/Em = 355/460 nm) . It is hydrolyzed by acidic ceramidase (AC) (appKm = 7.0 ?M; appVmax = 99.3 nM/min), N-acylethanolamine hydrolyzing acid amidase (appKm = 0.73 ?M; appVmax = 0.24 nM/min), and fatty acid amide hydrolase (FAAH) (appKm = 3.6 ?M; appVmax = 7.6 nM/min), but is not hydrolyzed by other ceramidases. RBM1-151 is useful for studying the basic biology of lipid amidase functions and for potential diagnostic/prognostic assessments in disorders involving AC, NAAA, or FAAH dysregulation, such as Farber disease and cancer.

• Smiles :

  O(C/C=C/C[C@H]([C@@H](NC(CCCCCCCCCCC)=O)C)O)C=1C=C2C(=CC1)C=CC(=O)O2

• Molecular Formula :

  C28H41NO5

• Molecular Weight :

  471.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3077081-47-8