EGFR-IN-151

CAT: 0013-GTR19258769-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19258769-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

EGFR-IN-151 (Compound 10) inhibits EGFR and its downstream signaling pathways ERK/STAT3. It effectively suppresses the proliferation of various lung cancer cells, with IC50 values of 11.7, 5.19, 7.32, and 1.53 μM for NCI-H1781, HCC827, NCI-H3255, and NCI-H1975, respectively. Additionally, EGFR-IN-151 hinders colony formation and cell migration in H1975, induces G1 phase cell cycle arrest, and triggers apoptosis in H1975 cells.

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Storage Conditions

-20°C

Notes

For research use only.

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EGFR-IN-151

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