JTE-151

• Target :

  ROR

• Related Pathways :

  Metabolism

• Bioactivity :

  JTE-151, a ROR? inhibitor, suppresses the overactive immune response by inhibiting ROR?, which is linked to the activation of Th17 cells. This action positions JTE-151 as a potential candidate for autoimmune disease research [1].

• Smiles :

  [C@@H](CC(NC1=C(Cl)C=C(C)C=C1)=O)(CCC(O)=O)C=2C(=C(ON2)[C@H]3C[C@@H](CC(C)(C)C)C3)C4CC4

• Molecular Formula :

  C28H37ClN2O4

• Molecular Weight :

  501.06

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1404380-58-0