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HPK1-IN-61

CAT: 0931-T212057-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212057-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
875638-86-1
Target
MAPK, Src, Bcr-Abl
Related Pathways
Cytoskeletal Signaling, MAPK, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
HPK1-IN-61 (Compound 1) serves as an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with a Ki of 0.4 nM, and also inhibits Abl with an IC50 of less than 0.51 nM. Additionally, HPK1-IN-61 displays inhibitory activity against LCK, with an IC50 of 24 nM.
Smiles
O=C(C=1C=C(C=CC1N)C2=CN=C3NC=C(C=4C=CC=CC4OC)C3=C2)N(C)C
Molecular Formula
C23H22N4O2
Molecular Weight
386.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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