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SPI-05

CAT: 0931-T211980-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211980-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5463-64-9
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
SPI-05 is a non-competitive inhibitor of SUMO-specific proteases (SENP1/2) with an IC50 of 60 ?M. It has potential applications in cancer research, particularly in the study of prostate cancer with SENP1 overexpression and solid tumors driven by hypoxia.
Smiles
O=S(=O)(O)C1=CC(N=NC2=CC=C(N)C=3C=CC=CC23)=CC=C1C=CC4=CC=C(N=NC5=CC=C(N)C=6C=CC=CC56)C=C4S(=O)(=O)O
Molecular Formula
C34H26N6O6S2
Molecular Weight
678.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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