SPI-05

• Target :

  E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination

• Bioactivity :

  SPI-05 is a non-competitive inhibitor of SUMO-specific proteases (SENP1/2) with an IC50 of 60 ?M. It has potential applications in cancer research, particularly in the study of prostate cancer with SENP1 overexpression and solid tumors driven by hypoxia.

• Smiles :

  O=S(=O)(O)C1=CC(N=NC2=CC=C(N)C=3C=CC=CC23)=CC=C1C=CC4=CC=C(N=NC5=CC=C(N)C=6C=CC=CC56)C=C4S(=O)(=O)O

• Molecular Formula :

  C34H26N6O6S2

• Molecular Weight :

  678.74

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  5463-64-9