ESI-05

• Target:

  CAMP|||Acyltransferase

• Related Pathways:

  Metabolism|||GPCR/G Protein

• Purity:

  0.98

• Bioactivity:

  ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 ?M) . ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.

• Smiles:

  Cc1ccc(cc1)S(=O)(=O)c1c(C)cc(C)cc1C

• Molecular Formula:

  C16H18O2S

• Molecular Weight:

  274.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  5184-64-5