SPI-112

• Target:

  Phosphatase

• Related Pathways:

  Metabolism

• Purity:

  >99.99%

• Bioactivity:

  SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.

• Smiles:

  OC(=O)c1cccc(N\N=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(F)cc2)c1

• Molecular Formula:

  C22H17FN4O5S

• Molecular Weight:

  468.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1051387-90-6